Ezrin Antikörper (N-Term)

Produktnummer ABIN7603214

Dieses Anti-Ezrin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ezrin in WB, IHC, IF, ICC und FACS. Geeignet für Human, Maus, Ratte und Affe.

Kurzübersicht für Ezrin Antikörper (N-Term) (ABIN7603214)

Target: Ezrin (EZR)

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ezrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-Ezrin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-Ezrin/EZR Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ezrin/EZR Antibody Picoband® (ABIN7603214). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Ezrin/EZR, which shares 85.7% amino acid (aa) sequence identity with mouse and rat EZR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Allenspach, E. J., Cullinan, P., Tong, J., Tang, Q., Tesciuba, A. G., Cannon, J. L., Takahashi, S. M., Morgan, R., Burkhardt, J. K., Sperling, A. I. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity 15: 739-750, 2001. 2. Bonilha, V. L., Rodriguez-Boulan, E. Polarity and developmental regulation of two PDZ proteins in the retinal pigment epithelium. Invest. Ophthal. Vis. Sci. 42: 3274-3282, 2001. 3. Faure, S., Salazar-Fontana, L. I., Semichon, M., Tybulewicz, V. L. J., Bismuth, G., Trautmann, A., Germain, R. N., Delon, J. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nature Immun. 5: 272-279, 2004.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Ezrin

Target: Ezrin (EZR)

Andere Bezeichnung: EZR

Hintergrund:

Synonyms: Dihydropyrimidine dehydrogenase [NADP (+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD

Tissue Specificity: Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.

Background: Ezrin also known as cytovillin or villin-2 is a protein that in humans is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Molekulargewicht: 81 kDa

Gen-ID: 7430

UniProt: P15311

Pathways: Maintenance of Protein Location