ARID3A Antikörper (N-Term)

Produktnummer ABIN7603197

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARID3A in WB, IP und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ARID3A Antikörper (N-Term) (ABIN7603197)

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARID3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-ARID3A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-ARID3A Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-ARID3A Antibody Picoband® (ABIN7603197). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ARID3A, which shares 95.8% amino acid (aa) sequence identity with mouse ARID3A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Alejo-Valle, O., Weigert, K., Bhayadia, R., Ng, M., Issa, H., Beyer, C., Emmrich, S., Schuschel, K., Ihling, C., Sinz, A., Zimmermann, M., Wickenhauser, C., Flasinski, M., Regenyi, E., Labuhn, M., Reinhardt, D., Yaspo, M. L., Heckl, D., Klusmann, J. H. The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood 139: 651-665, 2022. 2. Herrscher, R. F., Kaplan, M. H., Lelsz, D. L., Das, C., Scheuermann, R., Tucker, P. W. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 9: 3067-3082, 1995. 3. Kortschak, R. D., Reimann, H., Zimmer, M., Eyre, H. J., Saint, R., Jenne, D. E. The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome. Genomics 51: 288-292, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ARID3A

Target: ARID3A (AT Rich Interactive Domain 3A (BRIGHT-Like) (ARID3A))

Andere Bezeichnung: ARID3A

Hintergrund:

Synonyms: ARID3A, DRIL1, DRIL3, DRX, E2FBP1, AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1, E2F-binding protein 1

Background: AT-rich interactive domain-containing protein 3A is a protein that in humans is encoded by the ARID3A gene. This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.

Molekulargewicht: 80 kDa

Gen-ID: 1820

UniProt: Q99856

Pathways: Chromatin Binding