SLC22A3 Antikörper (N-Term)

Produktnummer ABIN7603188

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SLC22A3 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für SLC22A3 Antikörper (N-Term) (ABIN7603188)

Target: SLC22A3 (OCT3) (Organic Cation Transporter 3 (OCT3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-SLC22A3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-SLC22A3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SLC22A3 Antibody Picoband® (ABIN7603188). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC22A3, which shares 76.5% amino acid (aa) sequence identity with both mouse and rat SLC22A3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Lazar, A., Grundemann, D., Berkels, R., Taubert, D., Zimmermann, T., Schomig, E. Genetic variability of the extraneuronal monoamine transporter EMT (SLC22A3). J. Hum. Genet. 48: 226-230, 2003. 2. Nagano, T., Mitchell, J. A., Sanz, L. A., Pauler, F. M., Ferguson-Smith, A. C., Feil, R., Fraser, P. The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science 322: 1717-1720, 2008. 3. Sleutels, F., Zwart, R., Barlow, D. P. The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature 415: 810-813, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SLC22A3

Target: SLC22A3 (OCT3) (Organic Cation Transporter 3 (OCT3))

Andere Bezeichnung: SLC22A3

Hintergrund:

Synonyms: Smoothelin, SMTN, SMSMO

Tissue Specificity: Smooth muscle, contractile or vascular (for the long form).

Background: Solute carrier family 22 (extraneuronal monoamine transporter), member 3, also known as SLC22A3 or OCT3 is a protein that in humans is encoded by the SLC22A3 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene mediates potential-dependent transport of a variety of organic cations. It may play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.

Molekulargewicht: 61 kDa

Gen-ID: 6581

UniProt: O75751