MAP4K1 Antikörper (N-Term)

Produktnummer ABIN7603180

Der Kaninchen Polyklonal Anti-MAP4K1-Antikörper wurde für WB validiert. Er ist geeignet, MAP4K1 in Proben von Ratte zu detektieren.

Kurzübersicht für MAP4K1 Antikörper (N-Term) (ABIN7603180)

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP4K1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAP4K1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-MAP4K1/HPK1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MAP4K1/HPK1 Antibody Picoband® (ABIN7603180). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat MAP4K1/HPK1, which shares 88.2% and 100% amino acid (aa) sequence identity with human and mouse MAP4K1/HPK1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Rat
1. Hu, M. C.-T., Qiu, W. R., Wang, X., Meyer, C. F., Tan, T.-H. Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. Genes Dev. 10: 2251-2264, 1996. 2. Kiefer, F., Tibbles, L. A., Anafi, M., Janssen, A., Zanke, B. W., Lassam, N., Pawson, T., Woodgett, J. R., Iscove, N. N. HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway. EMBO J. 15: 7013-7025, 1996.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MAP4K1

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Andere Bezeichnung: Map4k1

Hintergrund:

Synonyms: Fascin-2, Retinal fascin, FSCN2

Tissue Specificity: Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.

Background: Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene. It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). The protein has been shown to play a role in JNK activation.

Molekulargewicht: 97 kDa

Gen-ID: 292763

UniProt: D3Z8I4

Pathways: T-Zell Rezeptor Signalweg, Signaling of Hepatocyte Growth Factor Receptor