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Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) Antikörper

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in WB. Geeignet für Ratte.
Produktnummer ABIN7603115

Kurzübersicht für Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) Antikörper (ABIN7603115)

Target

Alle Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) Antikörper anzeigen
Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)

Reaktivität

  • 5
  • 3
  • 2
Ratte

Wirt

  • 5
  • 1
Kaninchen

Klonalität

  • 6
Polyklonal

Konjugat

  • 6
Unkonjugiert

Applikation

  • 6
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 1
    • 1
    • 1
    N-Term

    Verwendungszweck

    Anti-ND4/Mtnd4 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-ND4/Mtnd4 Antibody (ABIN7603115). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of rat ND4/Mtnd4, which shares 82.3% amino acid (aa) sequence identity with mouse ND4/Mtnd4.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Rat
    1. Arizmendi, J. M., Skehel, J. M., Runswick, M. J., Fearnley, I. M., Walker, J. E. Complementary DNA sequences of two 14.5 kDa subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Complementation of the primary structure of the complex. FEBS Lett. 313: 80-84, 1992. 2. Attardi, G., Chomyn, A., Doolittle, R. F., Mariottini, P., Ragan, C. I. Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase. Cold Spring Harbor Symp. Quant. Biol. 1: 103-114, 1986. 3. Attardi, G., Chomyn, A., Montoya, J., Ojala, D. Identification and mapping of human mitochondrial genes. Cytogenet. Cell Genet. 32: 85-98, 1982.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)

    Andere Bezeichnung

    Mtnd4

    Hintergrund

    Synonyms: NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4, Mtnd4, mt-Nd4, Nd4

    Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.

    Background: NADH-ubiquinone oxidoreductase chain 4 is a protein that in humans is encoded by the mitochondrial gene MT-ND4. The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.

    Molekulargewicht

    48 kDa

    Gen-ID

    26201

    UniProt

    P05508
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