TACSTD2 Antikörper (Middle Region)

Produktnummer ABIN7603102

Der Kaninchen Polyklonal Anti-TACSTD2-Antikörper wurde für WB, FACS, IF und ICC validiert. Er ist geeignet, TACSTD2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TACSTD2 Antikörper (Middle Region) (ABIN7603102)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TACSTD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-TACSTD2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-TROP2/TACSTD2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TROP2/TACSTD2 Antibody Picoband® (ABIN7603102). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TROP2/TACSTD2, which shares 65% amino acid (aa) sequence identity with mouse and rat TACSTD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Calabrese, G., Crescenzi, C., Morizio, E., Palka, G., Guerra, E., Alberti, S. Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization. Cytogenet. Cell Genet. 92: 164-165, 2001. 2. Fornaro, M., Dell'Arciprete, R., Stella, M., Bucci, C., Nutini, M., Capri, M. G., Alberti, S. Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int. J. Cancer 62: 610-618, 1995. 3. Ha, N. T., Chau, H. M., Cung, L. X., Thanh, T. K., Fujiki, K., Murakami, A., Kanai, A. A novel mutation of M1S1 gene found in a Vietnamese patient with gelatinous droplike corneal dystrophy. Am. J. Ophthal. 135: 390-393, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TACSTD2

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Andere Bezeichnung: TACSTD2

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 15, Activator-recruited cofactor 105 kDa component, ARC105, CTG repeat protein 7a, Mediator complex subunit 15, Positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, TPA-inducible gene 1 protein, TIG-1, Trinucleotide repeat-containing gene 7 protein, MED15, ARC105, CTG7A, PCQAP, TIG1, TNRC7,

Tissue Specificity: Expressed in all tissues examined, including heart, brain, lung, spleen, thymus, pancreas, blood leukocyte and placenta. However, the level of expression varied, with highest expression in the placenta and peripheral blood and lowest in the pancreas and kidney.

Background: Tumor-associated calcium signal transducer 2, also known as Trop-2 and as epithelial glycoprotein-1 antigen (EGP-1), is a protein that in humans is encoded by the TACSTD2 gene This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Molekulargewicht: 45-65 kDa

Gen-ID: 4070

UniProt: P09758