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ARL6IP6 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARL6IP6 in WB, FACS, ICC, IF und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7603020

Kurzübersicht für ARL6IP6 Antikörper (Middle Region) (ABIN7603020)

Target

Alle ARL6IP6 Antikörper anzeigen
ARL6IP6 (ADP-Ribosylation-Like Factor 6 Interacting Protein 6 (ARL6IP6))

Reaktivität

Human, Maus, Ratte

Wirt

  • 10
  • 2
Kaninchen

Klonalität

  • 12
Polyklonal

Konjugat

  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ARL6IP6 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 1
    Middle Region

    Verwendungszweck

    Anti-ARL6IP6 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-ARL6IP6 Antibody Picoband® (ABIN7603020). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human ARL6IP6, identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
    1. Abumansour, I. S., Hijazi, H., Alazmi, A., Alzahrani, F., Bashiri, F. A., Hassan, H., Alhaddab, M., Alkuraya, F. S. ARL6IP6, a susceptibility locus for ischemic stroke, is mutated in a patient with syndromic cutis marmorata telangiectatica congenita. Hum. Genet. 134: 815-822, 2015. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 7/28/2015. 3. Ingley, E., Williams, J. H., Walker, C. E., Tsai, S., Colley, S., Sayer, M. S., Tilbrook, P. A., Sarna, M., Beaumont, J. G., Klinken, S. P. A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61-beta subunit. FEBS Lett. 459: 69-74, 1999.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    ARL6IP6 (ADP-Ribosylation-Like Factor 6 Interacting Protein 6 (ARL6IP6))

    Andere Bezeichnung

    ARL6IP6

    Hintergrund

    Synonyms: Interactor of HORMAD1 protein 1, Cancer/testis antigen 74, CT74, Coiled-coil domain-containing protein 36, CCDC36, IHO1

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: ADP ribosylation factor like GTPase 6 interacting protein 6 is a protein that in the humans is encoded by the ARL6IP6 gene. ARL6IP6 (ADP-ribosylation-like factor 6 interacting protein 6), also known as PFAAP1 (phosphonoformate immuno-associated protein 1), is a 226 amino acid multi-pass membrane protein that belongs to the ARL6IP6 family and is encoded by a gene that maps to human chromosome 2q23.3. A 2q23.3 novel microdeletion involving seven genes, including ARL6IP6, is linked to a proposed 2q23q24 microdeletion syndrome. Additional chromosome 2q deletions, which also include ARL6IP6, are linked to autism, developmental delays and communication impairment. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

    Molekulargewicht

    22 kDa

    Gen-ID

    151188

    UniProt

    Q8N6S5

    Pathways

    SARS-CoV-2 Protein Interaktom
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