SOX6 Antikörper (Middle Region)

Produktnummer ABIN7603012

Der Kaninchen Polyklonal Anti-SOX6-Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, SOX6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SOX6 Antikörper (Middle Region) (ABIN7603012)

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-SOX6 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-SOX6 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SOX6 Antibody Picoband® (ABIN7603012). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SOX6, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Batista-Brito, R., Rossignol, E., Hjerling-Leffler, J., Denaxa, M., Wegner, M., Lefebvre, V., Pachnis, V., Fishell, G. The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron 63: 466-481, 2009. 2. Cohen-Barak, O., Hagiwara, N., Arlt, M. F., Horton, J. P., Brilliant, M. H. Cloning, characterization and chromosome mapping of the human SOX6 gene. Gene 265: 157-164, 2001. 3. Connor, F., Wright, E., Denny, P., Koopman, P., Ashworth, A. The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res. 23: 3365-3372, 1995.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SOX6

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Andere Bezeichnung: SOX6

Hintergrund:

Synonyms: Tumor necrosis factor receptor superfamily member 13C, B-cell maturation defect, B-cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, CD268, Tnfrsf13c, Baffr, Bcmd, Br3

Tissue Specificity: Highly expressed in spleen and testis, detected at lower levels in lung and thymus.

Background: Transcription factor SOX-6 is a protein that in humans is encoded by the SOX6 gene. This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 92 kDa

Gen-ID: 55553

UniProt: P35712