TBX4 Antikörper (Middle Region)

Produktnummer ABIN7602998

Dieses Anti-TBX4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TBX4 in WB, FACS, ICC und IF. Geeignet für Human.

Kurzübersicht für TBX4 Antikörper (Middle Region) (ABIN7602998)

Target: TBX4 (T-Box 4 (TBX4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-TBX4 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-TBX4 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TBX4 Antibody Picoband® (ABIN7602998). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TBX4, which shares 81.8% amino acid (aa) sequence identity with mouse TBX4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Agulnik, S. I., Garvey, N., Hancock, S., Ruvinsky, I., Chapman, D. L., Agulnik, I., Bollag, R., Papaioannou, V., Silver, L. M. Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics 144: 249-254, 1996. 2. Bollag, R. J., Siegfried, Z., Cebra-Thomas, J. A., Garvey, N., Davison, E. M., Silver, L. M. An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus. Nature Genet. 7: 383-389, 1994. 3. Bongers, E. M. F., Van Bokhoven, H., Van Thienen, M.-N., Kooyman, M. A. P., Van Beersum, S. E. C., Boetes, C., Knoers, N. V. A. M., Hamel, B. C. J. The small patella syndrome: description of five cases from three families and examination of possible allelism with familial patella aplasia-hypoplasia and nail-patella syndrome. (Letter) J. Med. Genet. 38: 209-213, 2001.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu TBX4

Target: TBX4 (T-Box 4 (TBX4))

Andere Bezeichnung: TBX4

Hintergrund:

Synonyms: Inorganic pyrophosphatase 2, mitochondrial, Pyrophosphatase SID6-306, Pyrophosphate phospho-hydrolase 2, PPase 2, PPA2, HSPC124

Tissue Specificity: Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

Molekulargewicht: 60 kDa

Gen-ID: 9496

UniProt: P57082