Dieser Anti-HSPA4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HSPA4 in WB, IHC, ICC, IF und FACS. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7602896
Kurzübersicht für HSPA4 Antikörper (C-Term) (ABIN7602896)
Anti-HSPA4 Antibody Picoband® (ABIN7602896). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Aufreinigung
Immunogen affinity purified.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA4, which shares 95.2% amino acid (aa) sequence identity with both mouse and rat HSPA4.
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry, 2-5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human 1. Fathallah, D. M., Cherif, D., Dellagi, K., Arnaout, M. A. Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5. J. Immun. 151: 810-813, 1993. Note: Erratum: J. Immun. 151: 6616 only, 1993. 2. Gross, M. B. Personal Communication. Baltimore, Md. 10/22/2020. 3. Mohamed, B. A., Barakat, A. Z., Held, T., Elkenani, M., Muhlfeld, C., Manner, J., Adham, I. M. Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice. Am. J. Resp. Cell Molec. Biol. 50: 817-824, 2014.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
HSPA4
(Heat Shock 70kDa Protein 4 (HSPA4))
Andere Bezeichnung
HSPA4
Hintergrund
Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene. The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins. Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions. Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress.