DPYSL3 Antikörper (C-Term)

Produktnummer ABIN7602870

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DPYSL3 in WB. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für DPYSL3 Antikörper (C-Term) (ABIN7602870)

Target: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYSL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DPYSL3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-CRMP4/Dpysl3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-CRMP4/Dpysl3 Antibody Picoband® (ABIN7602870). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat CRMP4/Dpysl3, which shares 93.3% amino acid (aa) sequence identity with both human and mouse CRMP4/Dpysl3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Rat
1. Blasco, H., Bernard-Marissal, N., Vourc'h, P., Guettard, Y. O., Sunyach, C., Augereau, O., Khederchah, J., Mouzat, K., Antar, C., Gordon, P. H., Veyrat-Durebex, C., Besson, G., Andersen, P. M., Salachas, F., Meininger, V., Camu, W., Pettmann, B., Andres, C. R., Corcia, P., the French ALS Study Group. A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS. Hum. Mutat. 34: 953-960, 2013. 2. Byk, T., Dobransky, T., Cifuentes-Diaz, C., Sobel, A. Identification and molecular characterization of Unc-33-like phosphoprotein (Ulip), a putative mammalian homolog of the axonal guidance-associated unc-33 gene product. J. Neurosci. 16: 688-701, 1996. 3. Gaetano, C, Matsuo, T., Thiele, C. J. Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells. J. Biol. Chem. 272: 12195-12201, 1997.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu DPYSL3

Target: DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

Andere Bezeichnung: Dpysl3

Hintergrund:

Synonyms: Long-chain-fatty-acid--CoA ligase 3,6.2.1.3,Long-chain acyl-CoA synthetase 3,LACS 3,ACSL3,ACS3, FACL3, LACS3,

Tissue Specificity: Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.

Background: Dihydropyrimidinase-related protein 3 is an enzyme that in humans is encoded by the DPYSL3 gene. This gene encodes a protein that belongs to the TUC (TOAD-64/Ulip/CRMP) family of proteins. Members of this family are phosphoproteins that function in axonal guidance and neuronal differentiation during development and regeneration of the nervous system. A mutation in the human gene is associated with amyotrophic lateral sclerosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 62 kDa

Gen-ID: 25418

UniProt: Q62952