ARL3 Antikörper (C-Term)

Produktnummer ABIN7602850

Der Kaninchen Polyklonal Anti-ARL3-Antikörper wurde für WB, IF, FACS und ICC validiert. Er ist geeignet, ARL3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ARL3 Antikörper (C-Term) (ABIN7602850)

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-ARL3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-ARL3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-ARL3 Antibody Picoband® (ABIN7602850). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ARL3, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Alkanderi, S., Molinari, E., Shaheen, R., Elmaghloob, Y., Stephen, L. A., Sammut, V., Ramsbottom, S. A., Srivastava, S., Cairns, G., Edwards, N., Rice, S. J., Ewida, N., Alhashem, A., White, K., Miles, C. G., Steel, D. H., Alkuraya, F. S., Ismail, S., Sayer, J. A. ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition. Am. J. Hum. Genet. 103: 612-620, 2018. 2. Cavenagh, M. M., Breiner, M., Schurmann, A., Rosenwald, A. G., Terui, T., Zhang, C., Randazzo, P. A., Adams, M., Joost, H. G., Kahn, R. A. ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues. J. Biol. Chem. 269: 18937-18942, 1994. 3. Grayson, C., Bartolini, F., Chapple, J. P., Willison, K. R., Bhamidipati, A., Lewis, S. A., Luthert, P. J., Hardcastle, A. J., Cowan, N. J., Cheetham, M. E. Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3. Hum. Molec. Genet. 11: 3065-3074, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu ARL3

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Andere Bezeichnung: ARL3

Hintergrund:

Synonyms: ARL3, ARFL3, ADP-ribosylation factor-like protein 3

Background: ADP-ribosylation factor-like protein 3 is a protein that in humans is encoded by the ARL3 gene. Enables GDP binding activity, GTP binding activity, and microtubule binding activity. Involved in several processes, including cilium assembly, protein localization to cilium, and small GTPase mediated signal transduction. Acts upstream of or within post-Golgi vesicle-mediated transport. Located in several cellular components, including microtubule cytoskeleton, midbody, and photoreceptor connecting cilium. Implicated in Joubert syndrome and retinitis pigmentosa 83.

Molekulargewicht: 23 kDa

Gen-ID: 403

UniProt: P36405