PRDM4 Antikörper (AA 87-405)

Produktnummer ABIN7602584

Dieses Anti-PRDM4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRDM4 in ELISA, WB, IF und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PRDM4 Antikörper (AA 87-405) (ABIN7602584)

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-PRDM4 Antikörper

Bindungsspezifität: AA 87-405

Verwendungszweck: Anti-PRDM4 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRDM4 Antibody Picoband® (ABIN7602584). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRDM4 recombinant protein (Position: E87-R405).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Briknarova, K., Atwater, D. Z., Glicken, J. M., Maynard, S. J., Ness, T. E. The PR/SET domain in PRDM4 is preceded by a zinc knuckle. Proteins 79: 2341-2345, 2011. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/2/2015. 3. Yang, X.-H., Huang, S. PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1. Genomics 61: 319-325, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PRDM4

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Andere Bezeichnung: PRDM4

Hintergrund:

Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24

Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Background: The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.

Molekulargewicht: 88 kDa

Gen-ID: 11108

Pathways: Neurotrophin Signalübertragung