GSG2 Antikörper (AA 86-798)

Produktnummer ABIN7602576

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GSG2 in WB, ELISA, ICC, IF und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GSG2 Antikörper (AA 86-798) (ABIN7602576)

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-GSG2 Antikörper

Bindungsspezifität: AA 86-798

Verwendungszweck: Anti-GSG2/HASPIN Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-GSG2/HASPIN Antibody Picoband® (ABIN7602576). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GSG2/HASPIN recombinant protein (Position: R86-K798). Human GSG2/HASPIN shares 65% amino acid (aa) sequence identity with mouse GSG2/HASPIN.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Dai, J., Sultan, S., Taylor, S. S., Higgins, J. M. G. The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes Dev. 19: 472-488, 2005. 2. Higgins, J. M. G. The haspin gene: location in an intron of the integrin alpha-E gene, associated transcription of an integrin alpha-E-derived RNA and expression in diploid as well as haploid cells. Gene 267: 55-69, 2001. 3. Kelly, A. E., Ghenoiu, C., Xue, J. Z., Zierhut, C., Kimura, H., Funabiki, H. Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science 330: 235-239, 2010.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu GSG2

Target: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Andere Bezeichnung: HASPIN

Hintergrund:

Synonyms: HASPIN, GSG2, Serine/threonine-protein kinase haspin, EC 2.7.11.1, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear protein kinase

Background: Enables ATP binding activity and histone H3T3 kinase activity. Involved in several processes, including mitotic sister chromatid cohesion, mitotic spindle assembly checkpoint signaling, and protein localization to chromosome, centromeric region. Located in centrosome, nucleoplasm, and spindle.

Molekulargewicht: 88 kDa

Gen-ID: 83903