PYHIN1 Antikörper (AA 86-488)

Produktnummer ABIN7602574

Der Kaninchen Polyklonal anti-PYHIN1 Antikörper wird verwendet zum Nachweis von PYHIN1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, FACS, IHC, ICC und IF.

Kurzübersicht für PYHIN1 Antikörper (AA 86-488) (ABIN7602574)

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYHIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-PYHIN1 Antikörper

Bindungsspezifität: AA 86-488

Verwendungszweck: Anti-PYHIN1 Antibody

Homologie: Human PYHIN1 shares 45.6% amino acid (aa) sequence identity with mouse PYHIN1.

Produktmerkmale: Anti-PYHIN1 Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PYHIN1 recombinant protein (Position: K86-H488). Human PYHIN1 shares 45.6% amino acid (aa) sequence identity with mouse PYHIN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, HHuman, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PYHIN1

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Andere Bezeichnung: PYHIN1

Hintergrund:

Background: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: pyrin and HIN domain family member 1

Molekulargewicht: 55 kDa

Gen-ID: 149628

UniProt: Q6K0P9