Cytochrome C1 Antikörper (AA 85-325)

Produktnummer ABIN7602560

Dieses Anti-Cytochrome C1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cytochrome C1 in WB, ELISA, FACS, IF und ICC. Geeignet für Human.

Kurzübersicht für Cytochrome C1 Antikörper (AA 85-325) (ABIN7602560)

Target: Cytochrome C1 (CYC1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytochrome C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Cytochrome C1 Antikörper

Bindungsspezifität: AA 85-325

Verwendungszweck: Anti-CYC1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-CYC1 Antibody Picoband® (ABIN7602560). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CYC1 recombinant protein (Position: S85-K325).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Duncan, A. M. V., Ozawa, T., Suzuki, H., Rozen, R. Assignment of the gene for the cytochrome c1 subunit of the mitochondrial cytochrome bc-1 complex (CYC1) to human chromosome 8q24.3. Genomics 19: 400-401, 1994. 2. Fukuyama, R., Minoshima, S., Nishikimi, M., Ozawa, T., Suzuki, H., Shimizu, N. Assignment of cytochrome c1 gene to chromosome 8q24 distal to MYC. (Abstract) Cytogenet. Cell Genet. 58: 1929 only, 1991. 3. Gaignard, P., Menezes, M., Schiff, M., Bayot, A., Rak, M., Ogier de Baulny, H., Su, C.-H., Gilleron, M., Lombes, A., Abida, H., Tzagoloff, A., Riley, L., and 11 others. Mutations in CYC1, encoding cytochrome c1 subunit of respiratory chain complex III, cause insulin-responsive hyperglycemia. Am. J. Hum. Genet. 93: 384-389, 2013.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Cytochrome C1

Target: Cytochrome C1 (CYC1)

Andere Bezeichnung: CYC1

Hintergrund:

Synonyms: Oral-facial-digital syndrome 1 protein, Protein 71-7A, OFD1, CXorf5

Tissue Specificity: Widely expressed. Expressed in 9 and 14 weeks old embryos in metanephric mesenchyme, oral mucosa, lung, heart, nasal and cranial cartilage, and brain. Expressed in metanephros, brain, tongue, and limb.

Background: Cytochrome c1, heme protein, mitochondrial (CYC1), also known as UQCR4, MC3DN6, Complex III subunit 4, Cytochrome b-c1 complex subunit 4, or Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit is a protein that in humans is encoded by the CYC1 gene. This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6.

Molekulargewicht: 33 kDa

Gen-ID: 1537

UniProt: P08574