BCL11B Antikörper (AA 838-894)

Produktnummer ABIN7602551

Dieser Anti-BCL11B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von BCL11B in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für BCL11B Antikörper (AA 838-894) (ABIN7602551)

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL11B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BCL11B Antikörper

Bindungsspezifität: AA 838-894

Verwendungszweck: Anti-Ctip2/BCL11B Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ctip2/BCL11B Antibody (ABIN7602551). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Ctip2/BCL11B recombinant protein (Position: K838-S894).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu BCL11B

Target: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Andere Bezeichnung: BCL11B

Hintergrund:

Synonyms: Flap endonuclease 1, FEN-1, DNase IV, Flap structure-specific endonuclease 1, Maturation factor 1, MF1, hFEN-1

Tissue Specificity: Predominantly expressed in the liver (PubMed:11099417, PubMed:11452359). Low expression levels in the small intestine and colon (PubMed:11099417). Very low levels in other tissues, including brain, heart and spleen (PubMed:11452359).

Background: B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 130 kDa

Gen-ID: 64919

UniProt: Q9C0K0