PCCB Antikörper (AA 83-539)

Produktnummer ABIN7602549

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCCB in WB, ELISA, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PCCB Antikörper (AA 83-539) (ABIN7602549)

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCCB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-PCCB Antikörper

Bindungsspezifität: AA 83-539

Verwendungszweck: Anti-PCCB Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PCCB Antibody Picoband® (ABIN7602549). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PCCB recombinant protein (Position: D83-L539).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chloupkova, M., Maclean, K. N., Alkhateeb, A., Kraus, J. P. Propionic acidemia: analysis of mutant propionyl-CoA carboxylase enzymes expressed in Escherichia coli. Hum. Mutat. 19: 629-640, 2002. 2. Desviat, L. R., Clavero, S., Perez-Cerda, C., Navarrete, R., Ugarte, M., Perez, B. New splicing mutations in propionic acidemia. J. Hum. Genet. 51: 992-997, 2006. 3. Fenton, W. A., Gravel, R. A., Rosenblatt, D. S. Disorders of propionate and methylmalonate metabolism.In: Scriver, C. R., Beaudet, A. L., Sly, W. S., Valle, D. (eds.) : The Metabolic and Molecular Bases of Inherited Disease. Vol. II. (8th ed.) New York: McGraw-Hill (pub.) 2001. P. 2176.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PCCB

Target: PCCB (Propionyl CoA Carboxylase beta Polypeptide (PCCB))

Andere Bezeichnung: PCCB

Hintergrund:

Synonyms: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA, IL3R

Tissue Specificity: Brain.

Background: The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 55 kDa

Gen-ID: 5096

UniProt: P05166

Pathways: Monocarboxylic Acid Catabolic Process