Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch POLDIP2 in WB, ELISA, IP, IF, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN7602525
Kurzübersicht für POLDIP2 Antikörper (AA 81-324) (ABIN7602525)
Anti-POLDIP2 Antibody Picoband® (ABIN7602525). Tested in ELISA, Flow Cytometry, IP, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human POLDIP2 recombinant protein (Position: Q81-Q324). Human POLDIP2 shares 99.2% amino acid (aa) sequence identity with mouse POLDIP2.
POLDIP2
Reaktivität: Ratte
WB, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, - 1. Klaile, E., Muller, M. M., Kannicht, C., Otto, W., Singer, B. B., Reutter, W., Obrink, B., Lucka, L. The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J. Biol. Chem. 282: 26629-26640, 2007. 2. Liu, L., Rodriguez-Belmonte, E. M., Mazloum, N., Xie, B., Lee, M. Y. W. T. Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. J. Biol. Chem. 278: 10041-10047, 2003. 3. Xie, B., Li, H., Wang, Q., Xie, S., Rahmeh, A., Dai, W., Lee, M. Y. W. T. Further characterization of human DNA polymerase delta interacting protein 38. J. Biol. Chem. 280: 22375-22384, 2005.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
POLDIP2
(Polymerase (DNA-Directed), delta Interacting Protein 2 (POLDIP2))
Andere Bezeichnung
POLDIP2
Hintergrund
Polymerase delta-interacting protein 2 also known as Polymerase delta-interacting protein of 38 kDa (PDIP38) is encoded by the POLDIP2 gene in humans. This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants.