TTLL12 Antikörper (AA 8-634)

Produktnummer ABIN7602497

Produktdetails anti-TTLL12 Antikörper

Target: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Bindungsspezifität: AA 8-634

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTLL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Verwendungszweck: Anti-TTLL12 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TTLL12 Antibody Picoband® (ABIN7602497). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TTLL12 recombinant protein (Position: E8-Q634).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brants, J., Semenchenko, K., Wasylyk, C., Robert, A., Carles, A., Zambrano, A., Pradeau-Aubreton, K., Birck, C., Schalken, J. A., Poch, O., de Mey, J., Wasylyk, B. Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis. PLoS One 7: e51258, 2012. 2. Gross, M. B. Personal Communication. Baltimore, Md. 6/28/2021. 3. Ju, L.-G., Zhu, Y., Lei, P.-J., Yan, D., Zhu, K., Wang, X., Li, Q.-L., Li, X.-J., Chen, J.-W., Li, L.-Y., Wu, M. TTLL12 inhibits the activation of cellular antiviral signaling through interaction with VISA/MAVS. J. Immun. 198: 1274-1284, 2017.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TTLL12

Target: TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))

Andere Bezeichnung: TTLL12 (TTLL12 Produkte)

Hintergrund:

Synonyms: DAP3-binding cell death enhancer 1, Death ligand signal enhancer, DELE1, DELE, KIAA0141

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm.

Molekulargewicht: 75 kDa

Gen-ID: 23170

UniProt: Q14166