SORD Antikörper (AA 8-357)

Produktnummer ABIN7602485

Dieses Anti-SORD-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von SORD in WB, IHC und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SORD Antikörper (AA 8-357) (ABIN7602485)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SORD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 12B10G2

Produktdetails anti-SORD Antikörper

Bindungsspezifität: AA 8-357

Verwendungszweck: Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband® (monoclonal, 12B10G2)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband® (monoclonal, 12B10G2) (ABIN7602485). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Carr, I. M., Markham, A. F., Coletta, P. L. Identification and characterisation of a sequence related to human sorbitol dehydrogenase. Europ. J. Biochem. 245: 760-767, 1997. 2. Carr, I. M., Markham, A. F. Molecular genetic analysis of the human sorbitol dehydrogenase gene. Mammalian Genome 6: 645-652, 1995. 3. Carr, I. M., Whitehouse, A., Coletta, P. L., Markham, A. F. Structural and evolutionary characterization of the human sorbitol dehydrogenase gene duplication. Mammalian Genome 9: 1042-1048, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Andere Bezeichnung: SORD

Hintergrund:

Synonyms: T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, hTRiC5, CCT3, CCTG, TRIC5

Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Molekulargewicht: 40 kDa

Gen-ID: 6652

UniProt: Q00796