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SCNM1 Antikörper (AA 8-230)

Dieses Anti-SCNM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SCNM1 in ELISA, WB, IHC und FACS. Geeignet für Human, Ratte und Maus.
Produktnummer ABIN7602473

Kurzübersicht für SCNM1 Antikörper (AA 8-230) (ABIN7602473)

Target

Alle SCNM1 Antikörper anzeigen
SCNM1 (Sodium Channel Modifier 1 (SCNM1))

Reaktivität

  • 14
  • 4
  • 3
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 12
  • 2
Kaninchen

Klonalität

  • 12
  • 2
Polyklonal

Konjugat

  • 10
  • 2
  • 1
  • 1
Dieser SCNM1 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 6
    • 1
    • 1
    • 1
    • 1
    AA 8-230

    Verwendungszweck

    Anti-SCNM1 Antibody Picoband®

    Produktmerkmale

    Anti-SCNM1 Antibody Picoband® (ABIN7602473). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human SCNM1 recombinant protein (Position: D8-D230). Human SCNM1 shares 82.1% amino acid (aa) sequence identity with mouse SCNM1.
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Buchner, D. A., Trudeau, M., Meisler, M. H. SCNM1, a putative RNA splicing factor that modifies disease severity in mice. Science 301: 967-969, 2003. 2. Howell, V. M., Jones, J. M., Bergren, S. K., Li, L., Billi, A. C., Avenarius, M. R., Meisler, M. H. Evidence for a direct role of the disease modifier SCNM1 in splicing. Hum. Molec. Genet. 16: 2506-2516, 2007. 3. Iturrate, A., Rivera-Barahona, A., Flores, C. L., Otaify, G. A., Elhossini, R., Perez-Sanz, M. L., Nevado, J., Tenorio-Castano, J., Trivino, J. C., Garcia-Gonzalo, F. R., Piceci-Sparascio, F., De Luca, A., Martinez, L., Kalayci, T., Lapunzina, P., Altunoglu, U., Aglan, M., Abdalla, E., Ruiz-Perez, V. L. Mutations in SCNM1 cause orofaciodigital syndrome due to minor intron splicing defects affecting primary cilia. Am. J. Hum. Genet. 109: 1828-1849, 2022.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    SCNM1 (Sodium Channel Modifier 1 (SCNM1))

    Andere Bezeichnung

    SCNM1

    Hintergrund

    SCNM1 is a zinc finger protein and putative splicing factor. In mice, Scnm1 modifies phenotypic expression of Scn8a (MIM 600702) mutations.

    Molekulargewicht

    26 kDa

    Gen-ID

    79005
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