PRPF31 Antikörper (AA 73-488)

Produktnummer ABIN7602388

Der Kaninchen Polyklonal Anti-PRPF31-Antikörper wurde für WB, ELISA, IF, FACS und ICC validiert. Er ist geeignet, PRPF31 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PRPF31 Antikörper (AA 73-488) (ABIN7602388)

Target: PRPF31 (Pre-mRNA Processing Factor 31 (PRPF31))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRPF31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-PRPF31 Antikörper

Bindungsspezifität: AA 73-488

Verwendungszweck: Anti-PRPF31 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PRPF31 Antibody Picoband® (ABIN7602388). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRPF31 recombinant protein (Position: K73-K488).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Al-Maghtheh, M., Vithana, E., Tarttelin, E., Jay, M., Evans, K., Moore, T., Bhattacharya, S., Inglehearn, C. F. Evidence for a major retinitis pigmentosa locus on 19q13.4 (RP11), and association with a unique bimodal expressivity phenotype. Am. J. Hum. Genet. 59: 864-871, 1996. 2. Berson, E. L., Gouras, P., Gunkel, R. D., Myrianthopoulos, N. C. Dominant retinitis pigmentosa with reduced penetrance. Arch. Ophthal. 81: 226-234, 1969. 3. Deery, E. C., Vithana, E. N., Newbold, R. J., Gallon, V. A., Bhattacharya, S. S., Warren, M. J., Hunt, D. M., Wilkie, S. E. Disease mechanism for retinitis pigmentosa (RP11) caused by mutations in the splicing factor gene PRPF31. Hum. Molec. Genet. 11: 3209-3219, 2002.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PRPF31

Target: PRPF31 (Pre-mRNA Processing Factor 31 (PRPF31))

Andere Bezeichnung: PRPF31

Hintergrund:

Synonyms: Tumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, CD357, Tnfrsf18, Gitr

Tissue Specificity: Detected in thymus and in activated splenocytes.

Background: PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Molekulargewicht: 60 kDa

Gen-ID: 26121

Pathways: Ribonucleoprotein Complex Subunit Organization