KERA Antikörper (AA 73-115)

Produktnummer ABIN7602381

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KERA in WB und ELISA. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für KERA Antikörper (AA 73-115) (ABIN7602381)

Target: KERA (Keratocan (KERA))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KERA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KERA Antikörper

Bindungsspezifität: AA 73-115

Verwendungszweck: Anti-Keratocan/KTN/Kera Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Keratocan/KTN/Kera Antibody Picoband® (ABIN7602381). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Keratocan/KTN/Kera recombinant protein (Position: R73-K115).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Dudakova, L., Palos, M., Hardcastle, A. J., Liskova, P. Corneal endothelial findings in a Czech patient with compound heterozygous mutations in KERA. (Letter) Ophthalmic Genet. 35: 252-254, 2014. 2. Funderburgh, J. L., Perchellet, A. L., Swiergiel, J., Conrad, G. W., Justice, M. J. Keratocan (Kera), a corneal keratan sulfate proteoglycan, maps to the distal end of mouse chromosome 10. Genomics 52: 110-111, 1998. 3. Khan, A. O., Al-Saif, A., Kambouris, M. A novel KERA mutation associated with autosomal recessive cornea plana. Ophthal. Genet. 25: 147-152, 2004. Note: Erratum: Ophthal. Genet. 25: 289 only, 2004, Ophthal. Genet. 26: 195 only, 2005.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu KERA

Target: KERA (Keratocan (KERA))

Andere Bezeichnung: Kera

Hintergrund:

Synonyms: Protein Hook homolog 3, h-hook3, Hhk3, HOOK3

Tissue Specificity: Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).

Background: Keratocan (KTN) also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).

Molekulargewicht: 41 kDa

Gen-ID: 16545

UniProt: O35367

Pathways: Glycosaminoglycan Metabolic Process