Septin 12 Antikörper (AA 71-358)

Produktnummer ABIN7602363

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Septin 12 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Septin 12 Antikörper (AA 71-358) (ABIN7602363)

Target: Septin 12 (Sep12)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Septin 12 Antikörper

Bindungsspezifität: AA 71-358

Verwendungszweck: Anti-SEPTIN12 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SEPTIN12 Antibody Picoband® (ABIN7602363). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SEPTIN12 recombinant protein (Position: K71-F358).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hall, P. A., Jung, K., Hillan, K. J., Russell, S. E. H. Expression profiling the human septin gene family. J. Path. 206: 269-278, 2005. 2. Kuo, Y.-C., Lin, Y.-H., Chen, H.-I., Wang, Y.-Y., Chiou, Y.-W., Lin, H.-H., Pan, H.-A., Wu, C.-M., Su, S.-M., Hsu, C.-C., Kuo, P.-L. SEPT12 mutations cause male infertility with defective sperm annulus. Hum. Mutat. 33: 710-719, 2012. 3. Lin, Y.-H., Chou, C.-K., Hung, Y.-C., Yu, I.-S., Pan, H.-A., Lin, S.-W., Kuo, P.-L. SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos. Fertil. Steril. 95: 363-365, 2011.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Septin 12

Target: Septin 12 (Sep12)

Andere Bezeichnung: SEPTIN12

Hintergrund:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: Septin 12 is a protein that in humans is encoded by the SEPT12 gene. This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 45 kDa

Gen-ID: 124404