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WDR12 Antikörper (AA 7-396)

Dieses Anti-WDR12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WDR12 in WB, ELISA und FACS. Geeignet für Human.
Produktnummer ABIN7602332

Kurzübersicht für WDR12 Antikörper (AA 7-396) (ABIN7602332)

Target

Alle WDR12 Antikörper anzeigen
WDR12 (WD Repeat Domain 12 (WDR12))

Reaktivität

  • 27
  • 9
  • 8
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 27
Kaninchen

Klonalität

  • 27
Polyklonal

Konjugat

  • 17
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser WDR12 Antikörper ist unkonjugiert

Applikation

  • 27
  • 14
  • 8
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 7-396

    Verwendungszweck

    Anti-WDR12 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-WDR12 Antibody Picoband® (ABIN7602332). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human WDR12 recombinant protein (Position: R7-D396).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 10/27/2015. 2. Holzel, M., Rohrmoser, M., Schlee, M., Grimm, T., Harasim, T., Malamoussi, A., Gruber-Eber, A., Kremmer, E., Hiddemann, W., Bornkamm, G. W., Eick, D. Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. J. Cell Biol. 170: 367-378, 2005. 3. Kellner, M., Rohrmoser, M., Forne, I., Voss, K., Burger, K., Muhl, B., Gruber-Eber, A., Kremmer, E., Imhof, A., Eick, D. DEAD-box helicase DDX27 regulates 3-prime end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex. Exp. Cell Res. 334: 146-159, 2015.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    WDR12 (WD Repeat Domain 12 (WDR12))

    Andere Bezeichnung

    WDR12

    Hintergrund

    Synonyms: Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, Ppase, PPA1, IOPPP, PP

    Tissue Specificity: Expressed ubiquitously.

    Background: Ribosome biogenesis protein WDR12 is a protein that in humans is encoded by the WDR12 gene on chromosome 2. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.

    Molekulargewicht

    48 kDa

    Gen-ID

    55759
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