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HOXC13 Antikörper (AA 7-155)

Dieses Anti-HOXC13-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOXC13 in ELISA, WB, FACS, ICC und IF. Geeignet für Human.
Produktnummer ABIN7602314

Kurzübersicht für HOXC13 Antikörper (AA 7-155) (ABIN7602314)

Target

HOXC13 (Homeobox C13 (HOXC13))

Reaktivität

  • 10
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 7
  • 3
  • 1
Kaninchen

Klonalität

  • 8
  • 3
Polyklonal

Konjugat

  • 11
Dieser HOXC13 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-155

    Verwendungszweck

    Anti-HOXC13 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-HOXC13 Antibody Picoband® (ABIN7602314). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human HOXC13 recombinant protein (Position: L7-E155).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Farooq, M., Kurban, M., Fujimoto, A., Fujikawa, H., Abbas, O., Nemer, G., Saliba, J., Sleiman, R., Tofaili, M., Kibbi, A.-G., Ito, M., Shimomura, Y. A homozygous frameshift mutation in the HOXC13 gene underlies pure hair and nail ectodermal dysplasia in a Syrian family. Hum. Mutat. 34: 578-581, 2013. 2. Godwin, A. R., Capecchi, M. R. Hoxc13 mutant mice lack external hair. Genes Dev. 12: 11-20, 1998. 3. Lin, Z., Chen, Q., Shi, L., Lee, M., Giehl, K. A., Tang, Z., Wang, H., Zhang, J., Yin, J., Wu, L., Xiao, R., Liu, X., Dai, L., Zhu, X., Li, R., Betz, R. C., Zhang, X., Yang, Y. Loss-of-function mutations in HOXC13 cause pure hair and nail ectodermal dysplasia. Am. J. Hum. Genet. 91: 906-911, 2012.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    HOXC13 (Homeobox C13 (HOXC13))

    Andere Bezeichnung

    HOXC13

    Hintergrund

    Synonyms: Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, ATP-dependent RNA helicase #46, DEAH box protein 15, DHX15, DBP1, DDX15

    Tissue Specificity: Ubiquitous.

    Background: Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.

    Molekulargewicht

    35 kDa

    Gen-ID

    3229

    UniProt

    P31276
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