NSMCE4A Antikörper (AA 69-380)

Produktnummer ABIN7602302

Der Kaninchen Polyklonal anti-NSMCE4A Antikörper (ABIN7602302) detektiert spezifisch NSMCE4A in WB, ELISA, IF, FACS und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NSMCE4A Antikörper (AA 69-380) (ABIN7602302)

Target: NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSMCE4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-NSMCE4A Antikörper

Bindungsspezifität: AA 69-380

Verwendungszweck: Anti-NSMCE4A Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Anti-NSMCE4A Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NSMCE4A recombinant protein (Position: D69-Q380).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NSMCE4A

Target: NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))

Andere Bezeichnung: NSMCE4A

Hintergrund:

Background: Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene. NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.

Gene Full Name: NSE4A component of SMC5/6 complex

Molekulargewicht: 50 kDa

Gen-ID: 54780

UniProt: Q9NXX6

Pathways: Positive Regulation of Response to DNA Damage Stimulus