Western Blotting (WB), ELISA, Flow Cytometry (FACS)
Verwendungszweck
Anti-SYNPO2L Antibody Picoband®
Produktmerkmale
Anti-SYNPO2L Antibody Picoband® (ABIN7602256). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human SYNPO2L recombinant protein (Position: H66-E923). Human SYNPO2L shares 87.9% amino acid (aa) sequence identity with mouse SYNPO2L.
Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, - 1. Lubitz, S. A., Brody, J. A., Bihlmeyer, N. A., Roselli, C., Weng, L. C., Christophersen, I. E., ... & Lin, H. (2016). Whole exome sequencing in atrial fibrillation. PLoS genetics, 12(9), e1006284. 2. Van Eldik, W., Den Adel, B., Monshouwer-Kloots, J., Salvatori, D., Maas, S., Van Der Made, I., ... & Beqqali, A. (2017). Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart. PLoS One, 12(12), e0189139. 3. Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., ... & Kääb, S. (2012). Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nature genetics, 44(6), 670-675.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
SYNPO2L belongs to the synaptopodin family and is an actin-associated protein that may play a role in modulating actin-based shape. SYNPO2L is involved in the positive regulation of Rho protein signal transduction and the positive regulation of stress fiber assembly. Loss-of-function variants in the SYNPO2L gene are associated with atrial fibrillation