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PTCD3 Antikörper (AA 66-648)

Der Kaninchen Polyklonal Anti-PTCD3-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, PTCD3 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7602253

Kurzübersicht für PTCD3 Antikörper (AA 66-648) (ABIN7602253)

Target

PTCD3 (Pentatricopeptide Repeat Domain 3 (PTCD3))

Reaktivität

  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 7
Kaninchen

Klonalität

  • 7
Polyklonal

Konjugat

  • 7
Dieser PTCD3 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 2
    • 1
    • 1
    • 1
    AA 66-648

    Verwendungszweck

    Anti-PTCD3 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-PTCD3 Antibody Picoband® (ABIN7602253). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human PTCD3 recombinant protein (Position: D66-R648). Human PTCD3 shares 76.4% amino acid (aa) sequence identity with mouse PTCD3.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL
    1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    PTCD3 (Pentatricopeptide Repeat Domain 3 (PTCD3))

    Andere Bezeichnung

    PTCD3

    Hintergrund

    Synonyms: PTCD3, MRPS39, TRG15, Pentatricopeptide repeat domain-containing protein 3, mitochondrial, 28S ribosomal protein S39, mitochondrial, MRP-S39, Mitochondrial small ribosomal subunit protein mS39, Transformation-related gene 15 protein, TRG-15

    Background: Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol, mitochondrial matrix, and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.

    Molekulargewicht

    79 kDa

    Gen-ID

    55037
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