PTCD3 Antikörper (AA 66-648)

Produktnummer ABIN7602253

Produktdetails anti-PTCD3 Antikörper

Target: PTCD3 (Pentatricopeptide Repeat Domain 3 (PTCD3))

Bindungsspezifität: AA 66-648

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTCD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-PTCD3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-PTCD3 Antibody Picoband® (ABIN7602253). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PTCD3 recombinant protein (Position: D66-R648). Human PTCD3 shares 76.4% amino acid (aa) sequence identity with mouse PTCD3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PTCD3

Target: PTCD3 (Pentatricopeptide Repeat Domain 3 (PTCD3))

Andere Bezeichnung: PTCD3 (PTCD3 Produkte)

Hintergrund:

Synonyms: PTCD3, MRPS39, TRG15, Pentatricopeptide repeat domain-containing protein 3, mitochondrial, 28S ribosomal protein S39, mitochondrial, MRP-S39, Mitochondrial small ribosomal subunit protein mS39, Transformation-related gene 15 protein, TRG-15

Background: Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol, mitochondrial matrix, and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.

Molekulargewicht: 79 kDa

Gen-ID: 55037