BPIFA1 Antikörper (AA 64-256)

Produktnummer ABIN7602215

Produktdetails anti-BPIFA1 Antikörper

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Bindungsspezifität: AA 64-256

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPIFA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Anti-Plunc/BPIFA1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Plunc/BPIFA1 Antibody Picoband® (ABIN7602215). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Plunc/BPIFA1 recombinant protein (Position: L64-V256).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Bingle, C. D., Bingle, L. Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern. Biochim. Biophys. Acta 1493: 363-367, 2000. 2. Bingle, C. D., Craven, C. J. PLUNC: A novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. Hum. Molec. Genet. 11: 937-943, 2002. 3. Chu, H. W., Thaikoottathil, J., Rino, J. G., Zhang, G., Wu, Q., Moss, T., Refaeli, Y., Bowler, R., Wenzel, S. E., Chen, Z., Zdunek, J., Breed, R., Young, R., Allaire, E., Martin, R. J. Function and regulation of SPLUNC1 protein in mycoplasma infection and allergic inflammation. J. Immun. 179: 3995-4002, 2007.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu BPIFA1

Target: BPIFA1 (BPI Fold Containing Family A, Member 1 (BPIFA1))

Andere Bezeichnung: BPIFA1 (BPIFA1 Produkte)

Hintergrund:

Synonyms: IFNGR2 protein, Interferon gamma receptor 2, IFNGR2, mCG_11456

Tissue Specificity: Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Background: Palate, lung, and nasal epithelium clone protein[5] (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.

Molekulargewicht: 27 kDa

Gen-ID: 51297