Ribophorin II Antikörper (AA 64-174)

Produktnummer ABIN7602211

Der Kaninchen Polyklonal Anti-Ribophorin II-Antikörper wurde für WB, ELISA, IF, FACS und ICC validiert. Er ist geeignet, Ribophorin II in Proben von Human zu detektieren.

Kurzübersicht für Ribophorin II Antikörper (AA 64-174) (ABIN7602211)

Target: Ribophorin II (RPN2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ribophorin II Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-Ribophorin II Antikörper

Bindungsspezifität: AA 64-174

Verwendungszweck: Anti-RPN2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-RPN2 Antibody Picoband® (ABIN7602211). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RPN2 recombinant protein (Position: Q64-Q174).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barton, D. E., Crimaudo, C., Hortsch, M., Francke, U. The genes for ribophorins I and II are on human chromosomes 3q and 20 and mouse chromosomes 6 and 12, respectively. (Abstract) Cytogenet. Cell Genet. 46: 577 only, 1987. 2. Crimaudo, C., Hortsch, M., Gausepohl, H., Meyer, D. I. Human ribophorins I and II: the primary structure and membrane topology of two highly conserved round endoplasmic reticulum-specific glycoproteins. EMBO J. 6: 75-82, 1987. 3. Honma, K., Iwao-Koizumi, K., Takeshita, F., Yamamoto, Y., Yoshida, T., Nishio, K., Nagahara, S., Kato, K., Ochiya, T. RPN2 gene confers docetaxel resistance in breast cancer. Nature Med. 14: 939-948, 2008. Note: Erratum: Nature Med. 14: 1128 only, 2008.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Ribophorin II

Target: Ribophorin II (RPN2)

Andere Bezeichnung: RPN2

Hintergrund:

Synonyms: Fms-related tyrosine kinase 3 ligand ,Flt3lg ,

Background: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 2, also called ribophorin is an enzyme that in humans is encoded by the RPN2 gene. This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 69 kDa

Gen-ID: 6185

UniProt: P04844