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POC1A Antikörper (AA 6-371)

POC1A Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7602131
  • Target Alle POC1A Antikörper anzeigen
    POC1A (POC1 Centriolar Protein Homolog A (POC1A))
    Bindungsspezifität
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-371
    Reaktivität
    • 15
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 13
    • 2
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POC1A Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-POC1A Antibody Picoband®
    Produktmerkmale
    Anti-POC1A Antibody Picoband® (ABIN7602131). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human POC1A recombinant protein (Position: A6-D371). Human POC1A shares 91% amino acid (aa) sequence identity with mouse POC1A.
    Top Product
    Discover our top product POC1A Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hames, R. S., Hames, R., Prosser, S. L., Euteneuer, U., Lopes, C. A. M., Moore, W., Woodland, H. R., Fry, A. M. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells. Exp. Cell Res. 314: 574-589, 2008. 2. Keller, L. C., Geimer, S., Romijn, E., Yates, J., III, Zamora, I., Marshall, W. F. Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Molec. Biol. Cell 20: 1150-1166, 2009. 3. Sarig, O., Nahum, S., Rapaport, D., Ishida-Yamamoto, A., Fuchs-Telem, D., Qiaoli, L., Cohen-Katsenelson, K., Spiegel, R., Nousbeck, J., Israeli, S., Borochowitz, Z.-U., Padalon-Brauch, G., Uitto, J., Horowitz, M., Shalev, S., Sprecher, E. Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis syndrome is caused by a POC1A mutation. Am. J. Hum. Genet. 91: 337-342, 2012.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    POC1A (POC1 Centriolar Protein Homolog A (POC1A))
    Andere Bezeichnung
    POC1A (POC1A Produkte)
    Hintergrund
    POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.
    Molekulargewicht
    40 kDa
    Gen-ID
    25886
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