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POC1A Antikörper (AA 6-371)

Dieses Anti-POC1A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von POC1A in WB, IHC, ELISA, IF, FACS und ICC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7602131

Kurzübersicht für POC1A Antikörper (AA 6-371) (ABIN7602131)

Target

Alle POC1A Antikörper anzeigen
POC1A (POC1 Centriolar Protein Homolog A (POC1A))

Reaktivität

  • 18
  • 13
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 16
  • 2
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser POC1A Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-371

    Verwendungszweck

    Anti-POC1A Antibody Picoband®

    Produktmerkmale

    Anti-POC1A Antibody Picoband® (ABIN7602131). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human POC1A recombinant protein (Position: A6-D371). Human POC1A shares 91% amino acid (aa) sequence identity with mouse POC1A.
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hames, R. S., Hames, R., Prosser, S. L., Euteneuer, U., Lopes, C. A. M., Moore, W., Woodland, H. R., Fry, A. M. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells. Exp. Cell Res. 314: 574-589, 2008. 2. Keller, L. C., Geimer, S., Romijn, E., Yates, J., III, Zamora, I., Marshall, W. F. Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Molec. Biol. Cell 20: 1150-1166, 2009. 3. Sarig, O., Nahum, S., Rapaport, D., Ishida-Yamamoto, A., Fuchs-Telem, D., Qiaoli, L., Cohen-Katsenelson, K., Spiegel, R., Nousbeck, J., Israeli, S., Borochowitz, Z.-U., Padalon-Brauch, G., Uitto, J., Horowitz, M., Shalev, S., Sprecher, E. Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis syndrome is caused by a POC1A mutation. Am. J. Hum. Genet. 91: 337-342, 2012.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    POC1A (POC1 Centriolar Protein Homolog A (POC1A))

    Andere Bezeichnung

    POC1A

    Hintergrund

    POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.

    Molekulargewicht

    40 kDa

    Gen-ID

    25886
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