LHPP Antikörper (AA 6-270)

Produktnummer ABIN7602124

Der Kaninchen Polyklonal Anti-LHPP-Antikörper wurde für WB, ELISA, IF, FACS und ICC validiert. Er ist geeignet, LHPP in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für LHPP Antikörper (AA 6-270) (ABIN7602124)

Target: LHPP (Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase (LHPP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LHPP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-LHPP Antikörper

Bindungsspezifität: AA 6-270

Verwendungszweck: Anti-LHPP Antibody Picoband®

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Anti-LHPP Antibody Picoband® (ABIN7602124). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LHPP recombinant protein (Position: K6-K270).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hindupur, S. K., Colombi, M., Fuhs, S. R., Matter, M. S., Guri, Y., Adam, K., Cornu, M., Piscuoglio, S., Ng, C. K. Y., Betz, C., Liko, D., Quagliata, L., Moes, S., Jenoe, P., Terracciano, L. M., Heim, M. H., Hunter, T., Hall, M. N. The protein histidine phosphatase LHPP is a tumour suppressor. Nature 555: 678-682, 2018. 2. Neff, C. D., Packer, J. C. L., Chen, Y., Potter, J., Riley, R., Davenport, C., DeGrado Warren, J., Jammulapati, S., Bhathena, A., Choi, W. S., Kroeger, P. E., Metzger, R. E., Gutin, A., Skolnick, M. H., Shattuck, D., Katz, D. A. Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression. Molec. Psychiat. 14: 621-630, 2009. 3. Yokoi, F., Hiraishi, H., Izuhara, K. Molecular cloning of a cDNA for the human phospholysine phosphohistidine inorganic pyrophosphate phosphatase. J. Biochem. 133: 607-614, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu LHPP

Target: LHPP (Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase (LHPP))

Andere Bezeichnung: LHPP

Hintergrund:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: LHPP, also known as HDHD2B, is a 270 amino acid protein that exists as a homodimer and is a member of the HAD-like hydrolase superfamily. Expressed in liver, kidney and moderately in brain, LHPP is encoded by a gene located on 10, which houses over 1,200 genes and comprises nearly 4.5 % of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria

Molekulargewicht: 29 kDa

Gen-ID: 64077

UniProt: Q9H008