Nicalin Antikörper (AA 59-563)

Produktnummer ABIN7602104

Dieser Anti-Nicalin Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Nicalin in WB, ELISA, IHC, IF, ICC und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Nicalin Antikörper (AA 59-563) (ABIN7602104)

Target: Nicalin (NCLN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nicalin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-Nicalin Antikörper

Bindungsspezifität: AA 59-563

Verwendungszweck: Anti-NCLN Antibody Picoband®

Produktmerkmale: Anti-NCLN Antibody Picoband® (ABIN7602104). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NCLN recombinant protein (Position: Q59-Q563). Human NCLN shares 92.9% and 92.5% amino acid (aa) sequence identity with mouse and rat NCLN, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dettmer, U., Kuhn, P.-H., Abou-Ajram, C., Lichtenthaler, S. F., Kruger, M., Kremmer, E., Haass, C., Haffner, C. Transmembrane protein 147 (TMEM147) is a novel component of the nicalin-NOMO protein complex. J. Biol. Chem. 285: 26174-26181, 2010. 2. Haffner, C., Frauli, M., Topp, S., Irmler, M., Hofmann, K., Regula, J. T., Bally-Cuif, L., Haass, C. Nicalin and its binding partner Nomo are novel Nodal signaling antagonists. EMBO J. 23: 3041-3050, 2004. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 08/17/2021.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Nicalin

Target: Nicalin (NCLN)

Andere Bezeichnung: NCLN

Hintergrund: Nicalin is a protein that in humans is encoded by the NCLN gene. Enables ribosome binding activity. Involved in protein stabilization, regulation of protein complex stability, and regulation of protein-containing complex assembly. Located in endoplasmic reticulum membrane. Part of protein-containing complex.

Molekulargewicht: 63 kDa

Gen-ID: 56926

UniProt: Q969V3