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APLP1 Antikörper (AA 55-566)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch APLP1 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7602021

Kurzübersicht für APLP1 Antikörper (AA 55-566) (ABIN7602021)

Target

Alle APLP1 Antikörper anzeigen
APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Reaktivität

  • 34
  • 34
  • 15
  • 5
  • 4
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 47
  • 3
Kaninchen

Klonalität

  • 48
  • 2
Polyklonal

Konjugat

  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser APLP1 Antikörper ist unkonjugiert

Applikation

  • 36
  • 13
  • 13
  • 10
  • 8
  • 6
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-566

    Verwendungszweck

    Anti-APLP1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-APLP1 Antibody Picoband® (ABIN7602021). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human APLP1 recombinant protein (Position: Q55-Q566).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1.Lenkkeri, U., Kestila, M., Lamerdin, J., McCready, P., Adamson, A., Olsen, A., Tryggvason, K. Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1. Hum. Genet. 102: 192-196, 1998.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

    Andere Bezeichnung

    APLP1

    Hintergrund

    Synonyms: Fos-related antigen 1, FRA-1, FOSL1, FRA1

    Tissue Specificity: Adipocytes.

    Background: Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic absorbance. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.

    Molekulargewicht

    72 kDa

    Gen-ID

    333

    UniProt

    P51693

    Pathways

    cAMP Metabolic Process
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