SERPINA7 Antikörper (AA 55-389)

Produktnummer ABIN7602019

Der Kaninchen Polyklonal Anti-SERPINA7-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, SERPINA7 in Proben von Human zu detektieren.

Kurzübersicht für SERPINA7 Antikörper (AA 55-389) (ABIN7602019)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-SERPINA7 Antikörper

Bindungsspezifität: AA 55-389

Verwendungszweck: Anti-Thyroxine Binding Globulin/SERPINA7 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Thyroxine Binding Globulin/SERPINA7 Antibody Picoband® (ABIN7602019). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Thyroxine Binding Globulin/SERPINA7 recombinant protein (Position: R55-R389).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bertenshaw, R., Takeda, K., Refetoff, S. Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions. Am. J. Hum. Genet. 48: 741-744, 1991. 2. Buchanan, B. D., Hagen, G. A. Elevated thyroxine-binding globulin with X chromosome linked inheritance. Clin. Endocr. 11: 665-669, 1979. 3. Burr, W. A., Ramsden, D. B., Hoffenberg, R. Hereditary abnormalities of thyroxine-binding globulin concentration: a study of 19 kindreds with inherited increase or decrease of thyroxine-binding globulin. Quart. J. Med. 49: 295-313, 1980.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Andere Bezeichnung: SERPINA7

Hintergrund:

Synonyms: CD3 antigen, epsilon polypeptide, CD3e molecule, Cd3e, Cd3e_predicted, rCG_58471

Background: Thyroxine-binding globulin (TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Molekulargewicht: 50 kDa

Gen-ID: 6906

UniProt: P05543

Pathways: Hormone Transport