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SSR1 Antikörper (AA 53-286)

Dieses Anti-SSR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SSR1 in WB, IHC, ELISA, FACS, IF und ICC. Geeignet für Human, Maus, Ratte und Affe.
Produktnummer ABIN7601975

Kurzübersicht für SSR1 Antikörper (AA 53-286) (ABIN7601975)

Target

Alle SSR1 Antikörper anzeigen
SSR1 (Signal Sequence Receptor, alpha (SSR1))

Reaktivität

  • 23
  • 10
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte, Affe

Wirt

  • 17
  • 6
Kaninchen

Klonalität

  • 19
  • 4
Polyklonal

Konjugat

  • 23
Dieser SSR1 Antikörper ist unkonjugiert

Applikation

  • 23
  • 14
  • 8
  • 6
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-286

    Verwendungszweck

    Anti-TRAP alpha/TRAPA/SSR1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TRAP alpha/TRAPA/SSR1 Antibody Picoband® (ABIN7601975). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human SSR1 recombinant protein (Position: E53-E286).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Gross, M. B. Personal Communication. Baltimore, Md. 6/22/2012. 2. Hartmann, E., Prehn, S. The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges. FEBS Lett. 349: 324-326, 1994. 3. Hirama, T., Miller, C. W., Koeffler, H. P. Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation. FEBS Lett. 455: 223-227, 1999.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    SSR1 (Signal Sequence Receptor, alpha (SSR1))

    Andere Bezeichnung

    SSR1

    Hintergrund

    Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7

    Tissue Specificity: Expressed in basement membranes of lung and kidney. Muscle- and neuron-specific isoforms are found. Isoforms (y+) with the 4 AA insert and (z+8) isoforms with the 8 AA insert are all neuron-specific. Isoforms (z+11) are found in both neuronal and non-neuronal tissues.

    Background: Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    36 kDa

    Gen-ID

    6745

    UniProt

    P43307

    Pathways

    ER-Nucleus Signaling
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