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GOT1 Antikörper (AA 5-413)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GOT1 in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7601883

Kurzübersicht für GOT1 Antikörper (AA 5-413) (ABIN7601883)

Target

Alle GOT1 Antikörper anzeigen
GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Reaktivität

  • 75
  • 39
  • 24
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 80
  • 19
  • 4
  • 3
  • 3
Maus

Klonalität

  • 88
  • 21
Monoklonal

Konjugat

  • 62
  • 18
  • 9
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser GOT1 Antikörper ist unkonjugiert

Applikation

  • 92
  • 59
  • 31
  • 26
  • 23
  • 15
  • 13
  • 10
  • 9
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon

6B3B4
  • Bindungsspezifität

    • 15
    • 10
    • 9
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-413

    Verwendungszweck

    Anti-Aspartate Aminotransferase/GOT1 Antibody Picoband® (monoclonal, 6B3B4)

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Aspartate Aminotransferase/GOT1 Antibody Picoband® (monoclonal, 6B3B4) (ABIN7601883). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Aspartate Aminotransferase/GOT1 recombinant protein (Position: S5-Q413).

    Isotyp

    IgG2b
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Aitken, D. A., Ferguson-Smith, M. A. Gene dosage evidence for the regional assignment of the GOT-S structural gene locus to 10q24-10q25. Cytogenet. Cell Genet. 22: 468-471, 1978. 2. Creagan, R., Tischfield, J., McMorris, F. A., Chen, S.-H., Hirschi, M., Chen, T.-T., Ricciuti, F., Ruddle, F. H. Assignment of the genes for human peptidase A to chromosome 18 and cytoplasmic glutamic oxaloacetate transaminase to chromosome 10 using somatic-cell hybrids. Cytogenet. Cell Genet. 12: 187-198, 1973. 3. Doonan, S., Barra, D., Bossa, F. Structural and genetic relationships between cytosolic and mitochondrial isoenzymes. Int. J. Biochem. 16: 1193-1199, 1984.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

    Andere Bezeichnung

    GOT1

    Hintergrund

    Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115

    Background: Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

    Molekulargewicht

    43 kDa

    Gen-ID

    2805

    UniProt

    P17174

    Pathways

    Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process
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