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EXOSC8 Antikörper (AA 49-216)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EXOSC8 in WB, ELISA, IHC, IF, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7601850

Kurzübersicht für EXOSC8 Antikörper (AA 49-216) (ABIN7601850)

Target

Alle EXOSC8 Antikörper anzeigen
EXOSC8 (Exosome Component 8 (EXOSC8))

Reaktivität

  • 20
  • 2
  • 1
Human

Wirt

  • 17
  • 3
Kaninchen

Klonalität

  • 17
  • 3
Polyklonal

Konjugat

  • 16
  • 2
  • 1
  • 1
Dieser EXOSC8 Antikörper ist unkonjugiert

Applikation

  • 16
  • 13
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 49-216

    Verwendungszweck

    Anti-EXOSC8 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-EXOSC8 Antibody Picoband® (ABIN7601850). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human EXOSC8 recombinant protein (Position: A49-H216).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Boczonadi, V., Muller, J. S., Pyle, A., Munkley, J., Dor, T., Quartararo, J., Ferrero, I., Karcagi, V., Giunta, M., Polvikoski, T., Birchall, D., Princzinger, A., and 15 others. EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia. Nature Commun. 5: 4287, 2014. Note: Electronic Article. 2. Chen, C.-Y., Gherzi, R., Ong, S.-E., Chan, E. L., Raijmakers, R., Pruijn, G. J. M., Stoecklin, G., Moroni, C., Mann, M., Karin, M. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 107: 451-464, 2001. 3. Gross, M. B. Personal Communication. Baltimore, Md. 6/25/2014.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    EXOSC8 (Exosome Component 8 (EXOSC8))

    Andere Bezeichnung

    EXOSC8

    Hintergrund

    Synonyms: Homer protein homolog 3,Homer-3,HOMER3,

    Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

    Background: Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.

    Molekulargewicht

    35 kDa

    Gen-ID

    11340

    UniProt

    Q96B26

    Pathways

    SARS-CoV-2 Protein Interaktom
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