RASAL3 Antikörper (AA 48-925)

Produktnummer ABIN7601841

Produktdetails anti-RASAL3 Antikörper

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Bindungsspezifität: AA 48-925

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASAL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-RASAL3 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-RASAL3 Antibody Picoband® (ABIN7601841). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RASAL3 recombinant protein (Position: R48-Q925). Human RASAL3 shares 82.4% amino acid (aa) sequence identity with mouse RASAL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Gross, M. B. Personal Communication. Baltimore, Md. 9/18/2015. 2. Saito, S., Kawamura, T., Higuchi, M., Kobayashi, T., Yoshita-Takahashi, M., Yamazaki, M., Abe, M., Sakimura, K., Kanda, Y., Kawamura, H., Jiang, S., Naito, M., Yoshizaki, T., Takahashi, M., Fujii, M. RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells. Europ. J. Immun. 45: 1512-1523, 2015.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RASAL3

Target: RASAL3 (RAS Protein Activator Like 3 (RASAL3))

Andere Bezeichnung: RASAL3 (RASAL3 Produkte)

Hintergrund:

Synonyms: RASAL3, RAS protein activator like-3

Background: This gene belongs to the Ras GTPase-activating proteins (RasGAP) family and encodes a protein with pleckstrin homology (PH), C2, and Ras GTPase-activation protein (RasGAP) domains. This protein is localized near or at the plasma membrane when expressed exogenously. Reduced expression of this gene in some cell lines resulted in increased levels of the active form of Ras (Ras-GTP), suggesting that this gene may play a role in negatively regulating the Ras signaling pathway. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 112 kDa

Gen-ID: 64926