RTL1 Antikörper (AA 446-1327)

Produktnummer ABIN7601753

Produktdetails anti-RTL1 Antikörper

Target: RTL1 (Retrotransposon-Like 1 (RTL1))

Bindungsspezifität: AA 446-1327

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-RTL1 Antibody Picoband®

Produktmerkmale: Anti-RTL1 Antibody Picoband® (ABIN7601753). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RTL1 recombinant protein (Position: H446-R1327). Human RTL1 shares 68.3% amino acid (aa) sequence identity with mouse RTL1.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Davis, E., Caiment, F., Tordoir, X., Cavailli, J., Ferguson-Smith, A., Cockett, N., Georges, M., Charlier, C. RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus. Curr. Biol. 15: 743-749, 2005. Note: Erratum: Curr. Biol. 15: 884 only, 2005. 2. Kagami, M., Sekita, Y., Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y., Matsuoka, K., Takahashi, T., and 12 others. Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes. Nature Genet. 40: 237-242, 2008. 3. Seitz, H., Youngson, N., Lin, S.-P., Dalbert, S., Paulsen, M., Bachellerie, J.-P., Ferguson-Smith, A. C., Cavaille, J. Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nature Genet. 34: 261-262, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RTL1

Target: RTL1 (Retrotransposon-Like 1 (RTL1))

Andere Bezeichnung: RTL1 (RTL1 Produkte)

Hintergrund: RTL1 (retrotransposon like 1) is a retrotransposon derived protein coding gene. This gene is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. This gene is essential for maintenance of the fetal capillaries.

Molekulargewicht: 200 kDa

Gen-ID: 388015