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VPS41 Antikörper (AA 44-843)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VPS41 in ELISA, WB und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7601748

Kurzübersicht für VPS41 Antikörper (AA 44-843) (ABIN7601748)

Target

Alle VPS41 Antikörper anzeigen
VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))

Reaktivität

  • 18
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 16
  • 1
  • 1
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser VPS41 Antikörper ist unkonjugiert

Applikation

  • 8
  • 7
  • 4
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-843

    Verwendungszweck

    Anti-VPS41 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-VPS41 Antibody Picoband® (ABIN7601748). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human VPS41 recombinant protein (Position: Q44-R843).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL/mL, Human
    1. Asensio, C. S., Sirkis, D. W., Maas, J. W., Jr., Egami, K., To, T.-L., Brodsky, F. M., Shu, X., Cheng, Y., Edwards, R. H. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev. Cell 27: 425-437, 2013. 2. Cabrera, M., Langemeyer, L., Mari, M., Rethmeier, R., Orban, I., Perz, A., Brocker, C., Griffith, J., Klose, D., Steinhoff, H.-J., Reggiori, F., Engelbrecht-Vandre, S., Ungermann, C. Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J. Cell Biol. 191: 845-859, 2010. [PubMed: 21079247, images, related citations] [Full Text] 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/2/2009.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))

    Andere Bezeichnung

    VPS41

    Hintergrund

    Synonyms: E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein transferase PIAS2, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2, PIAS2, PIASX

    Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

    Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.

    Molekulargewicht

    99 kDa

    Gen-ID

    27072

    UniProt

    P49754
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