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VPS41 Antikörper (AA 44-843)

VPS41 Reaktivität: Human, Maus, Ratte ELISA, WB, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7601748
  • Target Alle VPS41 Antikörper anzeigen
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-843
    Reaktivität
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 13
    • 1
    • 1
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VPS41 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 5
    • 4
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-VPS41 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-VPS41 Antibody Picoband® (ABIN7601748). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human VPS41 recombinant protein (Position: Q44-R843).
    Isotyp
    IgG
    Top Product
    Discover our top product VPS41 Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL/mL, Human
    1. Asensio, C. S., Sirkis, D. W., Maas, J. W., Jr., Egami, K., To, T.-L., Brodsky, F. M., Shu, X., Cheng, Y., Edwards, R. H. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev. Cell 27: 425-437, 2013. 2. Cabrera, M., Langemeyer, L., Mari, M., Rethmeier, R., Orban, I., Perz, A., Brocker, C., Griffith, J., Klose, D., Steinhoff, H.-J., Reggiori, F., Engelbrecht-Vandre, S., Ungermann, C. Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J. Cell Biol. 191: 845-859, 2010. [PubMed: 21079247, images, related citations] [Full Text] 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/2/2009.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    Andere Bezeichnung
    VPS41 (VPS41 Produkte)
    Hintergrund

    Synonyms: E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein transferase PIAS2, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2, PIAS2, PIASX

    Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

    Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.

    Molekulargewicht
    99 kDa
    Gen-ID
    27072
    UniProt
    P49754
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