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FOXRED2 Antikörper (AA 44-623)

Dieses Anti-FOXRED2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FOXRED2 in ELISA und WB. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7601747

Kurzübersicht für FOXRED2 Antikörper (AA 44-623) (ABIN7601747)

Target

Alle FOXRED2 Antikörper anzeigen
FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reaktivität

Human, Maus, Ratte

Wirt

  • 9
Kaninchen

Klonalität

  • 9
Polyklonal

Konjugat

  • 5
  • 2
  • 1
  • 1
Dieser FOXRED2 Antikörper ist unkonjugiert

Applikation

  • 7
  • 3
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB)
  • Bindungsspezifität

    • 5
    • 2
    • 1
    • 1
    AA 44-623

    Verwendungszweck

    Anti-FOXRED2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-FOXRED2 Antibody Picoband® (ABIN7601747). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/25/2011. 2. Riemer, J., Appenzeller-Herzog, C., Johansson, L., Bodenmiller, B., Hartmann-Petersen, R., Ellgaard, L. A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc. Nat. Acad. Sci. 106: 14831-14836, 2009.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

    Andere Bezeichnung

    FOXRED2

    Hintergrund

    Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

    Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

    Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

    Molekulargewicht

    80 kDa

    Gen-ID

    80020

    Pathways

    SARS-CoV-2 Protein Interaktom
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