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Syntaphilin Antikörper (AA 43-482)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Syntaphilin in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7601724

Kurzübersicht für Syntaphilin Antikörper (AA 43-482) (ABIN7601724)

Target

Alle Syntaphilin (SNPH) Antikörper anzeigen
Syntaphilin (SNPH)

Reaktivität

  • 14
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 11
  • 3
Kaninchen

Klonalität

  • 13
  • 1
Polyklonal

Konjugat

  • 10
  • 2
  • 1
  • 1
Dieser Syntaphilin Antikörper ist unkonjugiert

Applikation

  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 43-482

    Verwendungszweck

    Anti-SNPH Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-SNPH Antibody Picoband® (ABIN7601724). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human SNPH recombinant protein (Position: Y43-Q482).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Lao, G., Scheuss, V., Gerwin, C. M., Su, Q., Mochida, S., Rettig, J., Sheng, Z.-H. Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly. Neuron 25: 191-201, 2000. 2. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    Syntaphilin (SNPH)

    Andere Bezeichnung

    SNPH

    Hintergrund

    Synonyms: Pannexin-2, PANX2

    Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

    Background: Syntaphilin is a protein that in humans is encoded by the SNPH gene. Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Molekulargewicht

    70 kDa

    Gen-ID

    9751

    UniProt

    O15079

    Pathways

    Synaptic Vesicle Exocytosis
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