SH2D4A Antikörper (AA 42-454)

Produktnummer ABIN7601695

Der Kaninchen Polyklonal Anti-SH2D4A-Antikörper wurde für WB, ELISA, IHC, IF, FACS und ICC validiert. Er ist geeignet, SH2D4A in Proben von Human und Ratte zu detektieren.

Kurzübersicht für SH2D4A Antikörper (AA 42-454) (ABIN7601695)

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH2D4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-SH2D4A Antikörper

Bindungsspezifität: AA 42-454

Verwendungszweck: Anti-SH2D4A Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SH2D4A Antibody Picoband® (ABIN7601695). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SH2D4A recombinant protein (Position: R42-E454).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dai, S., Zhao, Y., Ding, Q. A novel member of SH2A signaling protein family: cloning and characterization of SH2 gene. Chinese J. Med. Genet. 19: 458-462, 2002. 2. Lapinski, P. E., Oliver, J. A., Kamen, L. A., Hughes, E. D., Saunders, T. L., King, P. D. Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J. Immun. 181: 2019-2027, 2008. 3. Li, T., Li, W., Lu, J., Liu, H., Li, Y., Zhao, Y. SH2D4A regulates cell proliferation via the ER-alpha/PLC-gamma/PKC pathway. BMB Rep. 42: 516-522, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SH2D4A

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Andere Bezeichnung: SH2D4A

Hintergrund:

Synonyms: Tudor domain-containing protein 3, TDRD3

Tissue Specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Background: SH2 domain-containing protein 4A is a protein that in humans is encoded by the SH2D4A gene. Using exon trapping and exon linking at chromosome 8p22 cloned SH2D4A, which they called SH2A. The deduced 454-amino acid protein contains a single SH2 domain. RT-PCR and Northern blot analysis detected ubiquitous expression of 3 SH2A transcripts, as well as aberrant expression in some cancer cell lines. Dai et al. (2002) concluded that SH2A is a docking protein that may be involved in signal transduction.

Molekulargewicht: 50 kDa

Gen-ID: 63898

UniProt: Q9H788