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GIGYF2 Antikörper (AA 413-1299)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GIGYF2 in WB, IHC, ELISA, FACS, ICC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7601679

Kurzübersicht für GIGYF2 Antikörper (AA 413-1299) (ABIN7601679)

Target

Alle GIGYF2 Antikörper anzeigen
GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Reaktivität

  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 9
Kaninchen

Klonalität

  • 9
Polyklonal

Konjugat

  • 9
Dieser GIGYF2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 413-1299

    Verwendungszweck

    Anti-GIGYF2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-GIGYF2 Antibody Picoband® (ABIN7601679). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human GIGYF2 recombinant protein (Position: R413-Y1299).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bras, J., Simon-Sanchez, J., Federoff, M., Morgadinho, A., Januario, C., Ribeiro, M., Cunha, L., Oliveira, C., Singleton, A. B. Lack of replication of association between GIGYF2 variants and Parkinson disease. Hum. Molec. Genet. 18: 341-346, 2009. 2. Giovannone, B., Lee, E., Laviola, L., Giorgino, F., Cleveland, K. A., Smith, R. J. Two novel proteins that are linked to insulin-like growth factor (IFG-I) receptors by the Grb10 adapter and modulate IGF-I signaling. J. Biol. Chem. 278: 31564-31573, 2003. 3. Giovannone, B., Tsiaras, W. G., de la Monte, S., Klysik, J., Lautier, C., Karashchuk, G., Goldwurm, S., Smith, R. J. GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum. Molec. Genet. 18: 4629-4639, 2009.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

    Andere Bezeichnung

    GIGYF2

    Hintergrund

    Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29

    Tissue Specificity: Brain.

    Background: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    180 kDa

    Gen-ID

    26058

    UniProt

    Q6Y7W6

    Pathways

    Feeding Behaviour, SARS-CoV-2 Protein Interaktom
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