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GIGYF2 Antikörper (AA 413-1299)

GIGYF2 Reaktivität: Human WB, IHC, ELISA, FACS, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7601679
  • Target Alle GIGYF2 Antikörper anzeigen
    GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 413-1299
    Reaktivität
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 8
    Dieser GIGYF2 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Verwendungszweck
    Anti-GIGYF2 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-GIGYF2 Antibody Picoband® (ABIN7601679). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human GIGYF2 recombinant protein (Position: R413-Y1299).
    Isotyp
    IgG
    Top Product
    Discover our top product GIGYF2 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.25 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bras, J., Simon-Sanchez, J., Federoff, M., Morgadinho, A., Januario, C., Ribeiro, M., Cunha, L., Oliveira, C., Singleton, A. B. Lack of replication of association between GIGYF2 variants and Parkinson disease. Hum. Molec. Genet. 18: 341-346, 2009. 2. Giovannone, B., Lee, E., Laviola, L., Giorgino, F., Cleveland, K. A., Smith, R. J. Two novel proteins that are linked to insulin-like growth factor (IFG-I) receptors by the Grb10 adapter and modulate IGF-I signaling. J. Biol. Chem. 278: 31564-31573, 2003. 3. Giovannone, B., Tsiaras, W. G., de la Monte, S., Klysik, J., Lautier, C., Karashchuk, G., Goldwurm, S., Smith, R. J. GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling. Hum. Molec. Genet. 18: 4629-4639, 2009.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))
    Andere Bezeichnung
    GIGYF2 (GIGYF2 Produkte)
    Hintergrund

    Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29

    Tissue Specificity: Brain.

    Background: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.

    Molekulargewicht
    180 kDa
    Gen-ID
    26058
    UniProt
    Q6Y7W6
    Pathways
    Feeding Behaviour, SARS-CoV-2 Protein Interaktom
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