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CCDC99 Antikörper (AA 40-605)

Dieses Anti-CCDC99-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCDC99 in ELISA, WB, ICC, IF und FACS. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7601654

Kurzübersicht für CCDC99 Antikörper (AA 40-605) (ABIN7601654)

Target

Alle CCDC99 Antikörper anzeigen
CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Reaktivität

  • 25
  • 16
  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 38
  • 3
Kaninchen

Klonalität

  • 39
  • 2
Polyklonal

Konjugat

  • 16
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCDC99 Antikörper ist unkonjugiert

Applikation

  • 16
  • 14
  • 13
  • 13
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-605

    Verwendungszweck

    Anti-Spindly/SPDL1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Spindly/SPDL1 Antibody Picoband® (ABIN7601654). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Spindly/SPDL1 recombinant protein (Position: Q40-Q605).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Barisic, M., Sohm, B., Mikolcevic, P., Wandke, C., Rauch, V., Ringer, T., Hess, M., Bonn, G., Geley, S. Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation. Molec. Biol. Cell 21: 1968-1981, 2010. 2. Chan, Y. W., Fava, L. L., Uldschmid, A., Schmitz, M. H. A., Gerlich, D. W., Nigg, E. A., Santamaria, A. Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J. Cell. Biol. 185: 859-874, 2009. 3. Griffis, E. R., Stuurman, N., Vale, R. D. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J. Cell. Biol. 177: 1005-1015, 2007.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

    Andere Bezeichnung

    SPDL1

    Hintergrund

    Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

    Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

    Background: This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling.

    Molekulargewicht

    70 kDa

    Gen-ID

    54908
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