FLNB Antikörper (AA 397-701)

Produktnummer ABIN7601606

Dieser Anti-FLNB-Antikörper ist ein Maus-Monoklonal-Antikörper zum Nachweis von FLNB in WB, IHC, IF und ICC. Geeignet für Human.

Kurzübersicht für FLNB Antikörper (AA 397-701) (ABIN7601606)

Target: FLNB (Filamin B, beta (FLNB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FLNB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 11E2D2

Produktdetails anti-FLNB Antikörper

Bindungsspezifität: AA 397-701

Verwendungszweck: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2) (ABIN7601606). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu FLNB

Target: FLNB (Filamin B, beta (FLNB))

Andere Bezeichnung: FLNB

Hintergrund:

Synonyms: CMT2L, CRYAC, DHMN 2, DHMN2, E2IG1, H11, HMN 2, HMN2, HMN2A, HSB8, HSPB 8, HspB8

Tissue Specificity: Predominantly expressed in skeletal muscle and heart.

Background: Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Molekulargewicht: 278 kDa

Gen-ID: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location