SHROOM1 Antikörper (AA 371-807)

Produktnummer ABIN7601525

Dieses Anti-SHROOM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SHROOM1 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SHROOM1 Antikörper (AA 371-807) (ABIN7601525)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHROOM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SHROOM1 Antikörper

Bindungsspezifität: AA 371-807

Verwendungszweck: Anti-SHROOM1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SHROOM1 Antibody Picoband® (ABIN7601525). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SHROOM1 recombinant protein (Position: R371-D807).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hagens, O., Ballabio, A., Kalscheuer, V., Kraehenbuhl, J.-P., Schiaffino, M. V., Smith, P., Staub, O., Hildebrand, J., Wallingford, J. B. A new standard nomenclature for proteins related to Apx and Shroom. BMC Cell Biol. 7: 18, 2006. Note: Electronic Article. 2. Lee, C., Scherr, H. M., Wallingford, J. B. Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change. Development 134: 1431-1441, 2007. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. DNA Res. 8: 319-327, 2001.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Andere Bezeichnung: SHROOM1

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9, MED9, MED25,

Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Molekulargewicht: 91 kDa

Gen-ID: 134549

UniProt: Q2M3G4